Simparica TRIO

Simparica TRIO Chews for Dogs 44-88 lbs (20.1-40 kg) - Green 12 Chews

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Simparica Trio is the ultimate monthly chew that offers broad-spectrum protection for large dogs. This tasty, liver-flavored chew protects your dog from fleas, ticks, heartworms, roundworms, and hookworms with just one d…

MSRP: ¥33,536.89
¥26,829.20
(You save: ¥6,707.69 )
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Product Details

Simparica Trio is the ultimate monthly chew that offers broad-spectrum protection for large dogs. This tasty, liver-flavored chew protects your dog from fleas, ticks, heartworms, roundworms, and hookworms with just one dose each month.

Benefits & Features:

  • Fast-Acting Flea Control: Starts eliminating fleas within 4 hours and paralysis ticks within 24 hours.
  • Heartworm Prevention: Provides effective protection against deadly heartworm disease.
  • Comprehensive Worm Control: Targets and eliminates roundworms and hookworms, ensuring your dog stays healthy.
  • Convenient Monthly Chew: A simple, once-a-month chew that dogs love.
  • Not Suitable for Tapeworms: Additional treatment required for tapeworm protection.

Directions for Use:

  1. Weigh your dog to ensure accurate dosing.
  2. Administer one chew around the same day each month for continuous protection.
  3. If your dog is heartworm-positive, consult with your veterinarian before use.
  4. Use regularly to maintain protection against fleas, ticks, heartworm, roundworms, and hookworms.

Ingredients:

  • Sarolaner (flea and tick control)
  • Pyrantel (roundworm and hookworm control)
  • Moxidectin (heartworm prevention)

Weight Range & Product Guide:

  • Yellow: Small Breed Puppies 1.25 - 2.5 kg
  • Purple: Extra Small Dogs weighing between 2.6 - 5 kg
  • Orange: Small Dogs weighing between 5.1 - 10 kg
  • Blue: Medium Dogs weighing between 10.1 - 20 kg
  • Green: Large Dogs weighing between 20.1 - 40 kg
  • Red: Extra Large Dogs weighing between 40.1 - 60 kg

Safety Information:

  • Always ensure your dog's weight matches the product's recommended range for accurate dosing.
  • For use in heartworm-positive dogs, consult your veterinarian before starting treatment.
  • Keep out of reach of children.

Disclaimer: Our 12-packs are intended for multi-dog households and are supplied as multiple smaller packs (e.g., 2 x 6 packs or 4 x 3 packs). Please be aware that we cannot guarantee a 12-month expiry on these items. 

Reviews

43 Reviews

  • Works perfectly, half the price at the vet.
    5

    Posted by Whitney on Jan 26, 2026

    This stuff works, I can get it shipped to me, and I don’t have to make a vet appointment. Also way cheaper than the vets office charged me for it before. I will be ordering here from now on.

  • Great service and prices
    5

    Posted by Dolores Witko on Jan 14, 2026

    Friend referred me to this company and so thankful for her recommendation. I have shared as well with family and friends for affordable and reliable company. Shipping to NY from Sierrapetmeds 2 weeks so plan on ordering before you run out. Love the attention on my emails, always prompt and professional. Thank you.

  • Simparico
    5

    Posted by Dede on Jan 02, 2026

    Great product and prices

  • Simparica Trio
    5

    Posted by Debbi on Dec 29, 2025

    I have been ordering Simparica Trio from Sierra Pet Meds for several years. My large labs stay healthy with no ticks or fleas. Heart worm test come back from Vet all good.. Will continue to order.

  • Simparica Trio
    5

    Posted by DiAnn on Dec 01, 2025

    This is a great product because it’s a preventative for heartworm, ticks and fleas, all in one chewable tablet. I was referred to Sierra Pet Meds due to their competitive prices.

  • Simparica Trio
    5

    Posted by Tiffany Hood on Oct 06, 2025

    Great quality and works!

  • The best protection I have ever used for our dogs
    5

    Posted by Debbie Whipple on Aug 27, 2025

    I have been using this on four of our dogs. They have never had a flea, tick or worms. Getting them through Sierra has saved me vet expenses as well as a fortune on prevention meds . They are very quick and extremely affordable. Highly recommend This product and Sierra

  • Best Place to Purchase Meds
    5

    Posted by Elizabeth Simmons on Aug 18, 2025

    Sierra Pet Meds is THE BEST place to purchase pet meds. The price is so much lower than any other retailer, they deliver quickly, and they do not require a prescription for this simple medication.

  • Simparica
    5

    Posted by M S on Jul 13, 2025

    Works great. I appreciate the savings over other suppliers.

  • Simparica TRIO
    5

    Posted by Jesse on Jul 06, 2025

    Love the price and reputation.